Patti LuPone completed her training with the first class of the Drama Division of New York's Juilliard School, and began her career as a founding member of John Houseman's The Acting Company playing a variety of leading roles, both on and off-Broadway and on tour throughout the United States. Miss LuPone's memorable performances on the New York musical stage include Vera Simpson in the City Center Encores! production of Pal Joey, Reno Sweeney in Anything Goes (1988 Drama Desk Award, Tony nomination, Best Actress in a Musical), The Cradle Will Rock, Nancy in Oliver!, Eva Peron in Evita (1980 Tony and Drama Desk Awards- Best Actress in a Musical), Workin' and Rosamund in The Robber Bridegroom (1976 Tony and Drama Desk Award nominations, Best Featured Actress in a Musical).
Miss LuPone's other New York stage appearances include her debut with the New York Philharmonic playing Mrs. Lovett to George Hearn's Sweeney Todd in a concert version of the Stephen Sondheim musical, and critically-acclaimed performances in David Mamet's The Old Neighborhood, as Maria Callas in Terrence McNally's Tony Award-winning play Master Class and in her own concert Patti LuPone On Broadway, for which she won an Outer Critics Circle Award. Her Broadway stint starring in the Michael Frayn farce Noises Off was extremely successful.
In London, she created the role of Fantine in the the RSC production of Les Miserables, a role she subsequently played on the West End. For that performance, as well as the reprise of her performance in the London production of The Cradle Will Rock, she won an Olivier Award for Best Actress in a Musical. Miss LuPone created the role of Norma Desmond in Sunset Boulevard (1994 Olivier nomination, Best Actress in A Musical), and recreated her Broadway performance of Maria Callas in the West End production of Master Class.
Miss LuPone's film credits include Heist, City By The Sea, State and Main, Just Looking, Summer of Sam, The 24 Hour Woman, Family Prayers, Driving Miss Daisy and Witness. Her television credits include Sweeney Todd (PBS Great Performances), Touched By An Angel, PBS' Evening At The Pops with John Williams and Yo Yo Ma, Falcone, Bonanno: A Godfather's Story (Showtime); Frasier (1998 Emmy nomination); Law & Order, An Evening with Patti LuPone (PBS), the NBC movie Her Last Chance, Showtime's ACE Award and Emmy nominated The Song Spinner (Daytime Emmy nomination, Best Actress), The Water Engine, L.B.J., AMC's Remember WENN and ABC's Life Goes On, and TNT film Monday Night Mayhem. She has also made numerous recordings.